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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0cfc003b0bdbb8f86d0c25118f8dbf6c3d153315e685babfd9a99bf8bb9c097' 
  AND token = 'Gtyzh/bzXD49jPsjURlIoxncC0GHkouQU74zMFbCmyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}