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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52fc2b09c08be17034812460850e4774db600a4bc65ffa795d44e9c1d1bb350b' 
  AND token = 'J9IdBlPPMpuy2q+1GEk82x/YP7zedr5fzTS3OajbyY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}