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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad491e5b30ae285c839658d5f546089d066a2bcb38cf112499d3266a937bf2ac' 
  AND token = 'yEd2D0AONyyi0BbuCR56FND9vngB1EqCmrhwlh0I0yM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}