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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e4410fef1ad81dec91d593b19c7cce5e025a3cf07d242dc9f90ea4321c733e2' 
  AND token = 'CA9EZ6XQ/RaVyF2iICBLTp8w9iu3GZ0fo8ziJYnBLAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}