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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89639c74f1697e4e2a97bd1f198638ad6990d3bd93298e43e7c9ccf0ff639664' 
  AND token = '6QpfM7GFdwlrwgDE6WyPTkEWSJ9hRQ65iVH1ZUxmYkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}