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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '258f6e19a1c755723cfb4be25202f570fb81ee50b5b13aa155cc35ce3634acf6' 
  AND token = 'HrVGTeC1cF+NFkiMgYjsOkv2UeEBG+uDLtLRLoUPVrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}