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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a506ea8ce0000c3b2baefae9d8f3c25d263c53afc23f2e52aae9816d60d8180a' 
  AND token = 'e3QLjm2/B1TLaP+TD8AlllMcdAq/7Qso5bpLRIY0Qew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}