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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd54537208c123507f7f887dcec47cc3377c7a359bcaa551cbd2d441c7116c4af' 
  AND token = 'FOTReZXekXLgnkAZMCz5y4JngvQmrMN42muyRU1ynow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}