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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40b2cfdc12f87cccb9119e34ccca20ac4409cb6df4a0bfc1cb1042282b64ed41' 
  AND token = 'zFHP+HodPWZ+OVhIeypehOO4X+slrwEmoA1egRGtMpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}