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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6374cac0ce8a2b2714cab29c21bc36ea8994708391330e1362cf1cdf8af177c' 
  AND token = '+5St4jqtTwMx/6XAR7cBHncTbzja4cMECRg0Lydyejo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}