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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e5b1907cf4e476737493791128be740411d3fc655a624cfb5db24c8264af2a2' 
  AND token = 'UTDQGsNT7bSTNWTL5D+EyR0IAHm5+k7kGJE/nZK6hq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}