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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdc2c842b3874cc25ebefd39b4c6c5cb082e737cfc4380aa4e00a33d5296c730' 
  AND token = 'rLiw+gwc+s5WYlL+AuXe8kuB0ay3HZ5/gXdMSnbVGT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}