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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f6ae72e9ee63fe19da76ca3f13df661a2203b827e955a3f9cad158fa3a71778' 
  AND token = 'uWl58+hvPN96h7EjonkEnkhJOU/CqZgtC4U0XYT1/9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}