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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf0899e6d15f9db301cc1654739d56d28942657650af029799fbe5e0993a53e5' 
  AND token = 'As05GV9ccnHPsvCVynbd4kGhSprqkVPpQLA/u+YrJmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}