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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b77dd42d0980ff648619c173d1df4f5423910a26892f2b20789f76033cd1de6' 
  AND token = 'VODzmKG5MX2x+nw7WtAjrqtMgYueWpytppUd3xx0OV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}