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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f6c0f8950b29fdc6be8ee963522d6c144a754ae5c4617fdd2732d246777a026' 
  AND token = 'FfGYyqT45OKJX0i6BYj4yuqYbi2aj313St9STyzP3v4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}