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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45d26db713fd1d56fa6798ff3133ec9e12e4a17118e7a17309f36cff5d549d57' 
  AND token = 'ctcxFK/RaLa/u5o2c2L6S+IObWAa1Gj1DRpjRMf75jk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}