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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e7cc7b5b33faffbd4297e01d91f4347d3ec6fc789fd615a86ee37e317fdd1f5' 
  AND token = 'atz8wh7jBy2soR/kLbhp3vFzMgvx4hD3BvWvRLW3jQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}