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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e22b1143946c2e1cea8fa18ca31da67036181bb0e47fbf34e60a2f1e8cdbfeb' 
  AND token = 'aohSoLJYo3qloem8kNdpuz70yHV0tqEQCw3I0IWV4UQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}