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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d37023f2b8a3b70b0fe5a1dba7c0c0d994ade833283f4bf113815a175820472' 
  AND token = 'jtxDP82AwxZ0eUftrIrwz9LM2Y1bSRu9E5yACpsCkeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}