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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36ed7197a018a86f79e39eeb80333a385b6eaa4d63c4a9561b9344378277011a' 
  AND token = 'Bz5oHmRBS9JLo9JfcT1zXZanhuH2ovzRWXbCWffHCAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}