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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef1247248b9556d10d89cde8609bd3bf82e96e164d130a89fbf18cb61e19df63' 
  AND token = 'J4rgy00UDgVpWsY2/ewTaQ2fA+/iLgubS0uljpcX80U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}