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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '344ffb054be2412011ce98bdc54d3bb0d83c6b2a25bf55e1c63b43db56b44ecd' 
  AND token = 'OROX4e5anzTwiNCnBi2dMxiVvfbzw26S4mjnJZSgrfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}