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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f458d6a426701fa357c4b0c032029f469343defa450965dfec41e723cbcd7f5d' 
  AND token = '7UhxBtzuQU75oN5UIjgIBigS1UL1+6wizhVGP1w64K0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}