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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4be700280fa2378bf375ce8e23cb26530953ec8be3f5952b8353c96f9e6337d' 
  AND token = 'JyBxs7tlf+JXijUPEHulFVN1LanI3uWYL5R+wpCJGFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}