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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5d1fec25dca0bf5a8ecb57d89c8695d1c70f068d12abd43a14acd90a504d21a' 
  AND token = 'qEijAN7uHgQifsEOxvgSQGPeUUAuQJDBIBgy+o6mhW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}