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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f832a6450296ff133ce88669b4f9adcc70b122203a1baad2922500041c7ad69' 
  AND token = '6/u3USS6AxBkLSkju7+zbOzQNMtrLiZcEQMCitIUu08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}