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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5448de2a5155c6735d30fd1b9870138e2faf2da11bc68649269de1aa8dde28de' 
  AND token = 'HJPq58bhnPyC+5rJcZGL9bvn5LzRL/R0o1Lh5RXXgF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}