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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e5d02f46bc2aedc10fa9662aec36d974636184aa255e0b87022be1288a14ebe' 
  AND token = '8NcC0Cj2vrMoA4/pFqo+iW1fdujw1859y3y0ngWQc0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}