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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '722b0f6b6c0ad7ffcbd6f43d3d70ebe1601213162612bf4b3521ad66bcf53a94' 
  AND token = 'GWQf2u/zgHKVwZ/Pd+DZxir2WvPBN0E/DZugMrb3Pj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}