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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '183d6d3a9e7c41b8263e0f976ebf93e24ea17643a4af7f9e225b1e87d6ef6d1f' 
  AND token = 'dKssi2Szomz6JaUWSgXFivaMKz88cu7aGUJuG1ZzPwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}