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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5ea199f143fd0e54d47f0e013262bfb7f10291e57e29005b282b1c424e1f235' 
  AND token = 's6JoD/VdNHIQ5EIrc5HRtdx7R2d6jSi0vc0qbhfBT9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}