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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd27f9f35f1210831cfc6dcfcb26fdc0c8daae9122f38394e258693cc0ee0cb2' 
  AND token = '2+3cNxCuB5+xwWcdqQeI54RpLqrVBSMrBgLG0vjQdoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}