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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d10b13106ae9de874a8f4bb87412a15f26b57b7bdbc0b9e0e787f5c250dc7af' 
  AND token = '4s+sEo3s6zyz5XgRQNwcMgJ9xiZknb1DokU6AiHwOpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}