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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0597443416a91ec60529f52298a66982d8c3145397b3b210a04736b1d5fa5c35' 
  AND token = 'bUiqHSrBr8AQesU5h3kDoBmFvFZZchGKk5U4aX5xeNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}