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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f4d5af72c0af3ba171740104c29624ff3578881ac1a8b80f6d0a684f625518d' 
  AND token = 'XAFsihMJThDP3LS3ipOInLnOFPr4hiGnNRWv5SnqyBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}