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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b16b780a8000705bc08d1bf55cefabfb423474a8ca7dadf00c0b6d014a8c3b02' 
  AND token = 'zz3yzb2wAY48iPHUIbHLjVcmpgtIyk2cwO4IuRexmc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}