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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5fad51b499775c5fb802c9eeb86420dbc4e035384e7722131f72b7ee9cafc10' 
  AND token = '3aPj8C/dEDdlf7Cz/afTAN1PGB6fiOkKPuUP3xPfRV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}