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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52bc5e8a528a2d7ec3d67e6d9276c1d57cacd5e652e48ca06e7322363c9adf54' 
  AND token = 't5vBlPDm/lr3o7ttPhnruSUu6Mo4csHLQ1ARUxC1cxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}