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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce2127d88659b20e6a44940dc891b52bb64a1b7381e3ce4e150f47b7852b0635' 
  AND token = 'BJErCF8GBR9WVBJMreO/LjW5F2KxRmJyoBi/4c7nU60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}