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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '066a1f6459c050686783fb833ca42ea9f6abf7b99d0a0ec37a03b058b81f0aef' 
  AND token = '3gPMNcL75lkEPCd4mF1PAed9KxG2PofghPfGMv1QiOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}