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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6494cdf90fbe7b364a44cc8071280c2fd9d18e0aa692f0a53a87876b17e1b95f' 
  AND token = 'PykTJKQSMKYUTamY3ChLIg8pbG/ft0OWSpXg4ox0pfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}