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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '429a633b7bf0d554b15bff11bff1e9334157afe44ebd14967f740bf96a67ab20' 
  AND token = 'dW6GV+51ncijOBm7CRU/XMoFNnvB4/RTWxIbZ7h9MDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}