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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46972b2b0040cc43ae77198a391069e65c7140aa29b7476ae286360cd0abea3d' 
  AND token = 'nLBNz7/bHqgKQDl0UeA+DIyzDzu0zNfP3mEhSeJO4L0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}