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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfc46ef379dab2375f7060af55ecdb30b4cbef10dd9a1815e08145354db36e59' 
  AND token = 'NdOr3Fh3oZTdixtfJdJja2zuc/RSrM82a6w4MER81a0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}