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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '049b94d8f6682fef02ea5908dd611b8368eed369a0e35184e20e5f390c6db578' 
  AND token = '6QdCoJeVfxmxdN/xsCX37oieiA6nKKI3MroaEN8DowU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}