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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd443d13b1e72bffecd78fa52bcdeac815c5b62482a1978e05b0ca26e3a076f3d' 
  AND token = 'o+XUyeQemiYWMJ/03Q4D+PJL8/XCOCnooNpknj8e5s8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}