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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e13d1936f8f8435f32906c419ec1150e69762283668832b486d38df4affd351' 
  AND token = 'UplqV58dY/AUtCrtcrVc4CMtjyHuupOoQS+28C9Cj84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}