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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a0a452307d4b202f0c0902ddac95127e19d7bc6269f24f05aed40ebb73b1291' 
  AND token = '5uQRWy5qfUxGjO2mFMTLyzZ+9fZ7HNJs3g8Tt/xOPgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}