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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09eb2cdc3ba3e8fef78bc9b2b00e2fcd2d2d936efb65dc659780eda7a6400188' 
  AND token = 'ZgqCTVAazORTqGyUY6zd03kgWzhTTv9CauJc6bFPMM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}